Bladder cancer is one of the leading causes of hematuria. If you have hematuria and specifically clots in your urine it is somewhat likely you would have bladder cancer. Interestingly bladder cancer is often asymptomatic other than some bleeding. The bleeding can be brought about if you are on blood thinners such as aspirin, plavix or aggrenox for strokes or TIA prophylaxis. If you have atrial fibrillation or a history of blood clots you may be on coumadin or perhaps one of the newer anticoagulation medications such as pradaxa or xarelto. All of these medications can potentially unmask bleeding whether it be in the genitourinary tract or commonly in the gastrointestinal tract as well.
Bladder cancer if caught early can be treated by removal by cystoscopy and followed by intravesical BCG treatment as well to prevent recurrence of disease. As long as cancer tissue does not penetrate the muscular layer of the bladder you can rest assured you have localized disease which is certainly lucky. Others may not be so lucky with more advanced disease. Here is Dr. Bernard Bochner and Dr. Dean Bajorin talking about diagnosing bladder cancer and what not to overlook.